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Since sporozoites are essential for the infection process, our data reinforce the importance of breastfeeding and point to the potential of lactoferrin as a novel therapeutic agent for cryptosporidiosis. Physiologic concentrations of lactoferrin killed Cryptosporidium parvum sporozoites, but had no significant effect on oocysts viability or parasite intracellular development. In this study, we investigated the anticryptosporidial activity of human lactoferrin on different stages of Cryptosporidium. However, the effects of lactoferrin on the intestinal parasite Cryptosporidium have not been reported. It has showed bacteriostatic and antimicrobial activity in the intestine.

Lactoferrin is a glycoprotein found in breast milk. Current treatments for children suffering from cryptosporidiosis are suboptimal. Since sporozoites are essential for the infection process, our data reinforce the importance of breastfeeding and point to the potential of lactoferrin as a novel therapeutic agent for cryptosporidiosis.ĪB - Intestinal infection caused by Cryptosporidium is a major contributor to diarrhea morbidity and mortality in young children around the world. N2 - Intestinal infection caused by Cryptosporidium is a major contributor to diarrhea morbidity and mortality in young children around the world. © Copyright 2017 by The American Society of Tropical Medicine and Hygiene. There are no files associated with this item.T1 - Killing of cryptosporidium sporozoites by lactoferrinĪcknowledgments: JLP was supported by the Annual Medical Grant “Francisco Tejada and Semiramis Reátegui” from Universidad Peruana Cayetano Heredia.

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Show full item record Files in this item Files Hayley Watts, Graham Allcott - How to Fix Meetings Melinda Emerson - Become Your Own Boss in 12 Months Debra Koontz Traverso. These Champions included classroom teachers.

A 45-member team of 'Literacy Champions' advised DESE on the components, structure, and content of the guide.

Physiologic concentrations of lactoferrin killed Cryptosporidium parvum sporozoites, but had no significant effect on oocysts viability or parasite intracellular development. The development of the Mass Literacy guide spanned 9 months and was informed by a wide range of stakeholders, passionate about early literacy instruction and student learning.

Intestinal infection caused by Cryptosporidium is a major contributor to diarrhea morbidity and mortality in young children around the world.